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Polynucleotides activate creation of new collagen and elastin, which are responsible for youthful appearance of the skin. These substances are perfectly inherent in our bodies: they comprise nucleotides, basic building elements of the DNA and RNA nucleic acids. Skin biostimulation with polynucleotides is an innovative method of effective skin regeneration, hydration and rejuvenation, which many worldwide celebrities, including Jennifer Aniston and Kim Kardashian, have come to cherish.

What is polynucleotide skin biostimulation?

Skin biostimulation with polynucleotides is an innovative method of effective skin regeneration, hydration and rejuvenation. It consists of injections of concentrated polynucleotide extract from wild salmon DNA. This DNA material is safe and compatible with the human body, thus reducing the risk of immunological or allergic reactions or other adverse side effects.

The polynucleotides have an exceptional lifting effect, smooth the skin, prevent its sagging or drying, restore damaged skin and reduce skin imperfections such as enlarged pores or acne scars.

Is salmon sperm applied during the treatment?

The polynucleotides are obtained from a wild salmon DNA, therefore the term "salmon sperm facial". In reality, however, salmon sperm is not applied to the skin as such, only a clean material obtained from them and processed in a patented method.

Polynucleotide biostimulation - Croma PhilArt

In eveclinic, we work with exceptionally powerful PhilArt polynucleotide serums, which are intended for face, décolleté, neck and hand skin rejuvenation. An exceptional combination of unsaturated hyaluronic acid and polynucleotides guarantees long-lasting hydration and radiant look of the skin.

Main benefits of polynucleotide skin biostimulation:

  • natural lifting effect and skin firming
  • improving skin elasticity and firmness
  • smoothing visible signs of ageing, reducing fine lines and wrinkles
  • strengthening the skin barrier, restoring the natural protective skin layer
  • improving the skin structure, smoothing rough surfaces, reducing scars
  • reducing enlarged pores, reducing sebum formation
  • reducing swelling and dark circles under the eyes
  • improving skin hydration
  • giving the skin a homogeneous, healthy radiant tone

Who is polynucleotide treatment suitable for?

Polynucleotide biostimulation is suitable for women and men of all ages as a preventive or anti-ageing treatment or as an effective solution of the initial signs of ageing such as the loss of skin elasticity, wrinkles, uneven skin tone and structure, increased dryness or conversely sebum and the subsequent pore enlargement or damage by acne scars.

Which areas can I rejuvenate with salmon sperm?

Nucleotides can be used to treat various areas of the face, neck or body, including problematic eye areas where the skin ageing and imperfection usually appear the first. The nucleotides smooth and remove not only wrinkles and fine lines around the eyes, but also swelling and dark circles under the eyes, which present a frequent issue that is very hard to eliminate.

Polynucleotide biostimulation is also suitable for application in the scalp to thicken the hair and prevent hair loss.

Treatment process - Salmon Sperm Facial

The treatment is based on injections of an active substance (concentrated polynucleotide extract from a wild salmon DNA) into the skin, using a thin needle. The application immediately initiates a restoration process of damaged cells and stimulation as well as regeneration of tissues including fibroplasts responsible for collagen formation. The skin elasticity is significantly improved, excessive sebum formation regulated, pores become contracted and long-term healing and regenerative processes in the skin is started.

The effect of the treatment is visible immediately after application, but the maximum effect arrives gradually:

  • improving skin elasticity and hydration
  • forming new collagen
  • restoring new skin cells and growth acceleration
  • smoothing wrinkles and fine lines
  • intensive skin restoration
  • reducing swelling under the eyes and dark circles around the eyes
  • revitalizing the scalp when applied to it, thus restoring and strengthening hair growth

Recovery and post-treatment routine

The nucleotides are applied to the skin from one or multiple punctures, depending on the treated area and the selected application method. The needle marks may leave behind small bruises, reddening or swelling, which usually disappear within 3-5 days.

The needle is very thin, so the application is only slightly painful. Most of the patients tolerate it without problems. To increase comfort, an anaesthetic cream can be used.

After the treatment, you can more or less immediately return to the daily activities. However, we recommend abstaining from intensive sports or other power activities over the first 24 hours and from visiting swimming pools, saunas or steam baths for 1 week after the application. In the hot summer months, you should protect the treated areas with high SPF factor creams.

Frequency and number of treatments

To obtain an optimal effect, we recommend 2 to 4 treatments every 2 to 3 weeks.

Contraindications

The treatment is not suitable for persons with fish product allergy, pregnant and breastfeeding women or persons with active skin infection in the treated area.

Possible combinations with other treatments

1. Hyaluronic acid (wrinkle filling and hydration)

Polynucleotides promote regeneration and elasticity, while hyaluronic acid intensively hydrates and fills wrinkles. This combination provides an immediate and long-term rejuvenating effect.

2. Mesotherapy

Combined application with mesotherapy (e.g. vitamin cocktails) further promotes skin restoration, texture and radiance.

3. Chemical peeling or laser treatment

After exfoliating treatments, which disrupt the skin surface, polynucleotides can significantly accen/correction-and-smoothing-of-wrinkles/elerate regeneration and reduce irritation.

4. Mimic wrinkle removal using botulinum agents.

A combination of botulin and polynucleotides provides a more natural effect: the botulin agent loosens mimic wrinkles and polynucleotides improve skin quality around them.

5. Lifting treatments (e.g. thread lifting)

Polynucleotides promote regeneration after thread lifting treatments, accelerate healing and improve final effect of the skin repair.

Other lifting procedures >>

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FAQ

How long does the treatment take?

  • The treatment takes about 30-45 minutes depending on the treated area.

When do I see the results?

  • The first skin improvement is apparent after the first treatment, but the maximum effect comes gradually, after undertaking the recommended treatments (2-4 treatments).

Is the treatment painful?

  • The treatment is slightly unpleasant, but it is usually very well tolerated thanks to the use of very thin needles and anaesthetic cream.

How long does postoperative recovery take?

  • After the treatment, you can continue in your normal activities. Slight swelling, reddening or bruises in the injection area usually subside within 1–2 days.

Is the treatment suitable also for young people?

  • Yes, polynucleotide biostimulation is also suitable as a prevention of the first signs of skin ageing and as a skin structure improvement and hydration from the age of 25+.

What is the difference between polynucleotides and hyaluronic acid?

  • Hyaluronic acid primarily hydrates, while polynucleotides stimulate regeneration and collagen formation; they have a lifting effect. They provide a synergistic effect in a combination.

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